Referral Services provided by RCI

The RCI laboratory provides a reference service for hospital blood transfusion laboratories. The services provided by the RCI laboratory are listed below.

  • Provision of crossmatched blood for patients with complex antibodies.

  • Investigation of red cell antibodies

  • Investigation of Haemolytic Transfusion Reactions

  • ABO/Rh typing, including the investigation of blood group anomalies

  • Investigation of patient’s with positive Direct Antiglobulin Tests

  • Investigation of Autoimmune Haemolytic Anaemia

  • Investigation of Haemolytic Disease of the Fetus & Newborn (HDFN).

  • Antenatal screening for red cell antibodies to identify at risk pregnancies (antibody quantification or titration as appropriate).

  • Provision of suitable blood at delivery for at risk pregnancies

  • Phenotyping of donor red cells (Ordered via the IBTS electronic ordering system)

  • Clinical & scientific advice to hospital colleagues

  • Extended phenotyping for transfusion dependant patients and for patients with complex red cell antibodies.

  • Importation of rare blood for named patients.

  • Out of hours emergency on-call service


Additional services are provided by other support laboratories including; the Blood Group Genetics Laboratory (IBTS), the Molecular Diagnostics and Red Cell Reference laboratories (NHSBT, Filton) and RCI Sheffield (NHSBT).